Nature

Reducing attention bias toward negative emotional stimuli with transcranial random noise stimulation: a randomized, double-blind, sham-controlled, crossover study

Excessive attention bias interferes with daily life and contributes to various psychiatric conditions. Previous studies have demonstrated that anodal transcranial direct current stimulation (tDCS) ...
Nature

5-HTTLPR does not moderate the effect of attention bias modification for depression: a randomized sham-controlled trial

Attentional bias modification (ABM) is a digital intervention designed to modify negative attentional bias (AB [1]). AB is causally related to depressive symptoms [2] in all phases of Major depressive ...
EurekAlert!

Bias found when drug manufacturers fund clinical trials

COLUMBUS, Ohio – Psychiatric drugs are reported to be about 50% more effective in clinical trials funded by the drug’s manufacturer than when trials of the same drug are sponsored by other groups, new ...
ascopubs.org

Meta-Analysis of Bias in Non–Small Cell Lung Cancer External Control Arms That Use Real-World Progression-Free Survival as the End Point

Results from single-arm clinical trials can be contextualized by comparing against external controls (ECs) derived from real-world data (RWD). However, lack of randomization and differences in ...
Medical Xpress

Smartphone app developed by mental health researchers improves mental habits and functioning in randomized trial

In an effort to increase access to evidence-based interventions to help manage anxiety and depression, Mass General Brigham investigators have developed and tested a novel digital intervention called ...
The American Journal of Managed Care

Reassessing Antidepressant Efficacy: A Meta-Analysis of Control Group Outcomes in SSRI, Psilocybin, and Esketamine Trials

Psilocybin trials show poorer control group outcomes compared to SSRIs and esketamine, potentially inflating perceived efficacy due to expectancy bias and functional unblinding. Control group response ...