Radiotherapy-induced DNA damage can lead to apoptotic cell death and trigger an anti-tumor immune response via the cyclic GMP–AMP synthase–stimulator of interferon genes (cGAS–STING) pathway, which ...

Increasingly, cholesterol is implicated in diseases beyond the cardiovascular system. Major diseases of the gastrointestinal tract and liver are a case in point and are a focus of this Review.

Faulty lipid regulation in CLL patients impairs T-cell function, affecting treatment outcomes and resistance to current therapies. Differences in lipid metabolism between CLL patients and healthy ...

Sterols, such as cholesterol in our bodies or ergosterol in yeast cells, are among the most abundant lipids in eukaryotic cells, yet are synthesized through notoriously long, complex metabolic ...

The study identifies a new way of stopping bad fat from reaching the point inside liver cells where it is packaged for ...

Cholesterol drugs side effects go beyond cholesterol. New research links statins to brain changes, weight gain, and lower ...

In a recent review published in the journal Experimental & Molecular Medicine, researchers reviewed available literature on the role and mechanisms (molecular and pathological) by which cholesterol ...