Cyclophosphamide (CP), a widely used chemotherapeutic and immunosuppressive agent, has significant impacts on reproductive health in both males and females. A review published in the Journal of ...

While studying the effect of various cytotoxic natural products on different cancer cells, Koeberle from the Institute of Pharmaceutical Sciences at the University of Graz has discovered a previously ...

Cytotoxic drugs are seldom administered on their own, as these are usually combined with chemotherapy or radiotherapy. There is a rationale behind combining drugs rather than just using a single agent ...

Cytotoxic lymphocytes counter intracellular pathogens and cancer by recognizing and destroying infected or transformed target cells. The basis for their function is the cytolytic immune synapse, a ...

Pan-tumor circulating tumor DNA testing in the community oncology setting. This is an ASCO Meeting Abstract from the 2024 ASCO Annual Meeting I. This abstract does not include a full text component.

Cytotoxicity is a broad term that refers to the negative effects of chemical or environmental changes on cell health. Cells exposed to a cytotoxic stimulus may lose metabolic activity, experience ...

Cyclophosphamide (CP), a widely used chemotherapeutic and immunosuppressive agent, has significant impacts on reproductive health in both males and females. This review explores the mechanisms and ...