The ATR–ATRIP kinase complex safeguards genome integrity by coordinating cellular responses to DNA damage and replication stress. Two recent cryo-EM studies resolve the structural basis of ATR–ATRIP ...

A new discovery by researchers at the RIKEN Center for Biosystems Dynamics (BDR) in Japan upends decades of assumptions regarding DNA replication. Led by Ichiro Hiratani and colleagues, the ...

Before a cell can divide, it has to precisely duplicate its entire genetic information. However, the DNA in the cell exists as part of a DNA-protein complex known as chromatin. For this purpose, the ...

DNA replication and repair mechanisms constitute the foundation of genomic integrity, ensuring that genetic information is faithfully duplicated and maintained across cell generations. Replication ...

DNA is not an ionic bond—the ingenious structure that protects and 'opens' genetic informationWhen we think of DNA, we think ...

Why do human brains vary in size and shape, and how did our brains expand over evolutionary time to give us our enhanced ...

The Okazaki Fragments That Solved the Mystery of DNA Replication1. The Mystery That Could Not Be Solved by the Discovery of ...

Researchers at the MRC Laboratory of Medical Sciences (LMS) and collaborators have uncovered one of the earliest steps in DNA replication: the moment a cell first opens its DNA to begin making a copy ...

This voice experience is generated by AI. Learn more. This voice experience is generated by AI. Learn more. DNA doesn’t just carry information in its sequence; fleeting alternative folds like i‑DNA ...

Anthropic says its Claude AI system identified a previously uncharacterised enzyme system in bacteriophage DNA, but researchers are still investigating whether it can perform programmable genetic ...