This article was originally featured on Knowable Magazine. More than 1.5 billion years ago, a momentous thing happened: Two small, primitive cells became one. Perhaps more than any event—barring the ...

The nuclear pore complex (NPC) is a eukaryotic cellular structure that regulates bidirectional traffic of macromolecules across the nuclear envelope. Solving the intricate structure of this ~120-MDa ...

Studying the conformational dynamics of protein machines by cryo-electron microscopy (cryo-EM) is an important endeavor. In recent years, multiconformational structural studies have been achieved ...

Prokaryotic single-celled organisms, the ancestors of modern-day bacteria and archaea, are the most ancient form of life on our planet, first appearing roughly 3.5 billion years ago. The first ...

Scientists at St. Jude Children's Research Hospital have revealed how Fanzor2's divergence from bacterial ancestors may make it a useful tool for future genomic engineering endeavors. A revolution in ...

In many submerged regions, murky mud shelters strange life-forms that seem to be the key to one of the biggest mysteries of life on Earth. These creatures belong to a domain of life called the archaea ...

Elizabeth Kellogg, PhD, St. Jude Department of Structural Biology, used cryo-EM to study the evolutionary journey of Fanzor2, a compact eukaryotic genome-editing protein with huge potential. (MEMPHIS, ...

Scientists have revealed how Fanzor2's divergence from bacterial ancestors may make it a useful tool for future genomic engineering endeavors. A revolution in biomedicine is currently underway, driven ...