Aging causes organ dysfunction, chronic disease and death. Although interventions such as caloric restriction, young plasma and rapamycin extend healthspan in model organisms 1, potentially slowing ...

Upon intravenous administration, nanoparticles quickly become enveloped by plasma proteins, lipids, and sugars, forming a biomolecular corona that redefines their biological identity and directs ...

Scientists know that many proteins and pathways are involved in the development and progression of neurodegenerative conditions such as Alzheimer's disease, Parkinson's disease and frontotemporal ...

A large plasma proteomics study shows that aging patterns in specific cell types may help identify who is more vulnerable to ...

Cardiovascular disease (CVD) is the leading cause of death worldwide, accounting for approximately 30% of global mortality and imposing a substantial economic burden on society. Due to the high ...

A large, international team of medical researchers has found patterns developing with certain blood plasma protein levels that can lead to the development of sepsis in patients. In their study, ...

A proteomics- and machine learning (ML)-based precision prediction system enhances early risk stratification for diabetic retinal neurodegeneration (DRN), according to a study published online June 2 ...

Forty-five circulating proteins in plasma are linked to the risk for myocardial infarction (MI), showed a new study that confirms some known associations and identifies new ones. Several proteins are ...

How large, fully folded proteins can pass through cell membranes without destroying them has long been one of the open questions in cell biology. Using cryo-electron microscopy (cryo-EM), Leonid ...

An innovative gene-editing strategy could establish a new way for the body to manufacture therapeutic proteins—including certain kinds of highly potent antibodies that are naturally difficult to ...