Molecular machinery in cardiac mitochondria reacts to metabolic stress in unexpected way

In a recent study published in Nature Communications, researchers at Karolinska Institutet report that the molecular ...
Phys.org

New study examines ATP synthase at acidic state to reveal how the enzyme functions

A collaborative effort led by Stuti Sharma, Ph.D., Assistant Professor in the Department of Biochemistry & Cell Biology at Stony Brook University, resulted in a promising study toward a better ...
Nature

Ectopic ATP synthase stimulates the secretion of extracellular vesicles in cancer cells

Ectopic ATP synthase on the plasma membrane (eATP synthase) has been found in various cancer types and is a potential target for cancer therapy. However, whether it provides a functional role in tumor ...
Nature

Spatial and temporal dynamics of ATP synthase from mitochondria toward the cell surface

Ectopic ATP synthase complex (eATP synthase), located on cancer cell surface, has been reported to possess catalytic activity that facilitates the generation of ATP in the extracellular environment to ...