Proteins that respond to external stimuli function as molecular switches, playing a vital role in the precise regulation of biological processes. Therefore, if protein switches could be artificially ...

An antigen is any substance that can trigger an immune response in the body. Antigens are typically proteins or polysaccharides that are recognized as foreign or potentially harmful by the immune ...

The first Antibody-drug conjugate (ADC) was approved overa quarter-century ago, and today more than 20 have reached the clinic.

Many vaccines work by introducing a protein to the body that resembles part of a virus. Ideally, the immune system will produce long-lasting antibodies recognizing that specific virus, thereby ...

Efforts to contain the COVID-19 pandemic have largely focused on vaccine development and deployment. But how exactly do our immune systems respond to COVID-19 vaccines? The major response occurs in ...

In tumor-bearing mouse models, anti-programmed death-ligand 1 antibodies with stronger Fcγ receptor binding were associated with higher antidrug antibody levels and anaphylaxis, with tumor-associated ...

K. pneumoniae is frequently the source of hospital-acquired infections and, due to the widespread use of antibiotics in these settings, has also acquired numerous resistance genes. In fact, over ...

Cost Effectiveness of Interval Cytoreductive Surgery With Hyperthermic Intraperitoneal Chemotherapy in Stage III Ovarian Cancer on the Basis of a Randomized Phase III Trial Pegaspargase (PEG-ASP) has ...

Antibodies that primarily target the N-terminal domain (NTD) have less ability to protect against delta strains than antibodies that primarily target the receptor-binding domain (RBD). Efforts to ...